Create Detabase website in html css javascript and back-end programming full responsive

Creating a responsive, database-driven website using HTML, CSS, JavaScript, and a back-end programming language such as PHP or Python, would require several steps:

1. Create the HTML structure for the website using a responsive layout such as Bootstrap or Foundation to ensure that the website adjusts to different screen sizes.

2. Use CSS to style the website and make it visually appealing.

3. Use JavaScript to add interactivity to the website, such as form validation and dynamic content updates.

4. Create a back-end script in PHP or Python to handle the database operations, such as connecting to the database, inserting, updating, and retrieving data.

5. Use a database management system such as MySQL or MongoDB to store and retrieve data.

6. Use AJAX to make asynchronous requests from JavaScript to the back-end script, to avoid reloading the whole page when the user interacts with the website.

7. Test the website on different screen sizes and devices to ensure that it is fully responsive.

8. Implement security measures to protect the website from malicious attacks.

It's worth noting that this is a high-level overview and the complexity of such a task varies depending on the functionality that you want to achieve with your website. It's suggested to start small and gradually build upon it.